MP/84 antigen expression in biopsy sections of patients with benign and malignant tumours

ABSTRACT

This study indicates that MP/84 antigen is expressed in the kidney sections of renal cell carcinoma and it is not expressed in any other acute or malignant tissues sections. MP/84 is an antigen expressed in diseased kidney sections such as IgA nephropathy, membranous and minimal change. It was noted from previous studies that it is also expressed in BeWo choriocarcinoma cell line and not in other cell tested. The pathogenesis mechanism could be due to the secretion of cytokines by the renal cells