Intralesional theory of cutaneous leishmaniasis with hypertonic sodium chloride solution

ABSTRACT

One hundred and fifty-two liesions of cutaneous leishinaniasis in 70 patients were treated with intralesional hypertonic sodium chloride [116 lesions], intralesional pentostam [26 lesions], and 10 lesions were left untreated as controls. The injections were given at 10 day intervals and patients were followed-up for 42 days. intralesional hypertonic sodium chloride solution was shown to be very effective local therapy [88.2% cure rate], and was as effective as intralesional pentostam [88.9% cure rate]. In both types of therapy most lesions needed either one or two injections, and rarely more injections were needed. Mild improvement was noticed after 10 days of the first injection, while the cure was noticed within 2-6 weeks