Chronic unclassified arteritis, a non-arteriosclerotic arterio-occlusive disease with a distinct clinicohistopathological entity

ABSTRACT

9 patients with characteristic clinical and histopathological features which are different from the known types of arteritis in literature were described. All the patients were non-diabetic males [mean age = 42.2 years]. The commonly affected arterial segment was the ilio-common femoral and the femoro-popliteal segments, with otherwise angiographically healthy arterial tree. Angiographically normal run-off arteries were always present. Operatively, the arteries has a fleshy thick wall which was rather friable with a variable degree of periarterial fibrosis. Immunohistopathological findings included a thick internal and external elastic lamina with variable patterns of chronic inflammatory cell infiltration and immune deposits of IgG and complement [C3] mainly