Impaired hepatic function tests after streptokinase for acute myocardial infarction

ABSTRACT

Comparing the results of livers function tests for 50 patients with acute myocardial infarction, of which 25 patients received strepto- kinase and the other 25 patients matched in age, sex, and clinical presentation did not receive streptokinase, on admission and after one week. There was a significant increment in the serum total bilirubin, alkaline phosphotase and GGT in both groups after one week. While SGPT was no significantly elevated in the control group while it was very highly significantly elevated at one week in SK group. Both group had comparable results after one week with not significant difference. So the results of this study concluded that hepatic dysfunction was more marked after SK administration. The exact mechanism of these dysfunction are not yet fully elucidated