Synthesis of some new pyrazolones as potent anti-inflammatory agents

ABSTRACT

A series of 1,2-diphenyl-3,5-bis [alkyl and /or aryl amino] pyrazolium perchlorates [2a-e] 1,2-diphenyl-3-substituted 5-pyrazolones 3a-c, 4a-c, 6 and 1,2 diphenyl-5-pyrazolone Schiff's bases 7a-d were prepared. Some of the prepared compounds were tested for their antiinflammatory, analgesic, and antipyretic activities