Effect of dinothrombium tinctorium on the reproductive function of immature male rat

ABSTRACT

Administration of Dinothrombium tinctorium 100 mg/kg/day oral for 8 weeks caused no significant increase in weight, prostate glands, seminal vesicle, epididymis, testosterone level in serum as well as in testis tissue. The sperm concentration and sperm motility have also no significant increase, serum transaminase/phosphate, serum protein/cholestrol/lipid/bilirubin, blood urea and blood sugar remain unaltered. The histological observations of the testis indicated no significant changes in the diameter of the seminiferous tubules, Sertoli cells, Leydig's cells, spermatocyte, spermatid and spermatozoa