Langerhans' cell histiocytosis [LCH]

ABSTRACT

Twelve patients with biopsy proven Langerhans cell histiocytosis [LCH] were diagnosed between 1983-1993 at King Fahd University Hospital, AI-Khobar, Saudi Arabia. There were eight males and four females with a ratio of 2 1. Three has localized lesions and nine had disseminated disease with or without organ dysfunction. Bone involvement was seen in nine patients [75%] and five had organ dysfunction. Follow-up was from two to ten years M5 yrs. Two patients died, three had recurrences and four [33%] had disabilities. Overall disease free survival was [83%]