Plasma C3c level in patients with type II diabetes mellitus with microabluminuria

ABSTRACT

The study included 10 NIDDM patients with microalbuminuria, 10 NIDDM patients and 10 age matched normal controls. All were subjected to clinical examination, E.C.G., biochemical assessment for blood sugar, total serum cholesterol, serum creatinine, and serum C3c. Results revealed significant lowering of serum C3c in diabetic patients with microalbuminuria than controls [M. 76.43 +/- 15 and 95.75 + 22.23, respectively] [p < 0.036] and non significant reduction in diabetic patients without microalbuminuria [M. 87.327 = 21.22 mg/dl] [p < 0.398]. There was an inverse correlation between plasma level of C3c and each of total serum cholesterol [p < 0.001], degree of microalbuminuria [p < 0.0001] and ischemic heart disease [p < 0.002]