Study of bone age and serum osteocalcin in congenital heart disease

ABSTRACT

Bone age and serum osteocalcin were studied in 31 children with congenital heart disease [9 cyanotic and 22 acyanotic] aged between 6/12 and 10 years together with 31 normal parallel controls. Weight, height and head circumference were also measured for all cases and control. Showed significant growth retardation [in weight and height] in all children with congenital heart disease particularly in the cyanotice group. Significant delay in bone age was also noticed in patients [total and cyanotic in comparison with controls. Serum osteocalcin was a higher in cyanotic patients in comparison with controls, yet the difference was not statistically significant