Study of carcinoembryonic antigen in bilharzial and non bilharzial carcinoma of the urinary bladder

ABSTRACT

Urine and serum carcinoembryonic antigen [C.E.A] were determined in 43 patients with bilharzial bladder carcinoma [22 patients] and non- bilharzial bladder carcinoma [21 patients] as well as in 10 normal controls. Significant increase of both urine and serum C.E.A. levels in bladder carcinoma patients compared to control levels was detected. Urinary C.E.A. Was elevated in 86% of bilharzial bladder carcinomal versus 62% in non-bilharzial bladder carcinoma while serum C.E.A. Was raised in 39% of bilharzial bladder carcinoma versus 10.5% in non- bilharzial carcinoma. The mean urinary C.E.A. in bilharzial carcinoma was higher than that of non-bilharzial carcinoma but the difference was not statistically significant. There was a definite relationship between urine C.E.A. And the stage of malignancy, the higher the stage, the higher the level of urine C.E.A. No relationship could be detected between the stage of malignancy and serum C.E.A. or between the grade of malignancy and urine or serum C.E.A levels