Renal impairment in jaundiced full term neonates

ABSTRACT

This study included eighty-five full term newborns with unconjugated hyperbilirubinemia due to ABO and RH incompatibility as well as twenty healthy age and sex matched full term newborns as a control group. None of the cases showed any other stress factor which may cause renal failure e.g. septicemia, asphyxia or diabetic mother. Abdominal ultrasonography was done to exclude cases renal abnormalities. All cases were subjected to full clinical examination. Laboratory investigations of blood samples were taken at the 15th day then at the 30th day of postnatal life for blood culture, Coomb's test, blood urea and serum sodium, potassium, creatinine and uric acid. Blood groups were determined for babies and their mothers. Urine samples were taken at the 5th, 15th and 30th day of postnatal life for urine analysis, total protein, microalbumin, B2-microglobulin, urinary creatinine, sodium and potassium