Leucocyte analysis in Coulter STKS in Leucocytosis and malignant blood diseases

ABSTRACT

Two hundred and thirty-eight selected patients were used to study the leukocyte analysis in the coulter STKS in malignant disease and reactive leukocytosis compared with visual method as a reference method. Group I included 141 patients with leukocytosis [more than 12.0 X 10 9/L] were used to study the total leukocytic count and the differential count. Group II included 97 patients with malignant blood disease and were used to study the suspect flag. It was found that the difference between the results of STKS and that of manual method in the total leukocytic count is highly significant due to multiple technical inherent errors which are liable to occur in counting method. The differential count of the STKS correlated well with the visual methods as regards to lymphocytes, monocytes and eosinophils. A significant difference was found between the results of STKS and visual method as regards neutrophils [underestimation of count] and the basophils [over estimation]