Synthesis and pharmacological activity of benzodipyran derivatives
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 21-35
en Inglés
| IMEMR
| ID: emr-40776
ABSTRACT
1,2-dihydropyrano [3,2-g] [1] benzopyran-5-one derivatives IV a,b, VII and 1,2,3,4-tetrahydropyrano [3,2,g] [1] benzopypran-5-one derivatives VIII a-k were synthesized from the o-hydroxyaldehyde II. Compounds IVb, V, VIb, VII, VIIIb,c were tested for analgesic anti-inflammatory and ulcerogenic effects. Compounds VIIIb,c, VIb and VII were found to be potent analgesics with minimal ulcerogenic effect except VIb. None of the tested compounds was found to have anti-inflammatory activity
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Benzopiranos
/
Analgésicos
Límite:
Animales
Idioma:
Inglés
Revista:
Egypt. J. Pharm. Sci.
Año:
1996
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