Cerebrospinal fluid, sodium, potassium and bicarbonate concentrations in congenital hydrocephalus children

The objective of this investigation is to throw the light on the biochemical changes of cerebrospinal fluid electrolytes, sodium, potassium and bicarbonate in normal control and congenital hydrocephalus CSF samples of children, their ages ranged from 0.6 to 3 years]. These electrolytes regulate hydration and dehydration intracellular. The results revealed a nonsignificant decreasing of sodium with slightly decreasing in potassium and bicarbonate compared with control CSF samples. Although there is a significant decrease in Na + and K + [P <0.01] and Na+/HCO3 [P <0.01] in hydrocephalus patients, while insignificant decreasing of K + and HCO3 in the same patients. The results suggested that decreasing of CSF electrolytes is relatively to defect of brain membrane permeability or humoral contribution