Clinicopathological assessment of kaposi's sarcoma

ABSTRACT

Out of 20 cases of Kaposi's sarcoma [KS] received in Dermatology and Venereology Department [1980-1996], 19 cases [95%] were classic form and one case [5%] was KS associated with immunosuppressive therapy after renal transplant. There was a male preponderance. The commonest sites affected were the lower limbs and the commonest lesion detected was plaque either singly, or in combination with nodules and patchlesions. Ultrastructural examination of 6 lesions [3 plaques and 3 nodules] proved vascular endothelial origin of tumor cells. Image DNA cytophotometric analysis of 14 lesions [8 plaques and 6 nodules] revealed aneuploid cell population