Synthesis of 6- [4- [substituted - amino] phenyl] - 4,5 -dihydropyridazin-3 [H] ones as potential positive inotropic agents
Egyptian Journal of Pharmaceutical Sciences. 1997; 38 (4-6): 319-331
en Inglés
| IMEMR
| ID: emr-44551
ABSTRACT
A series of 6-[4-[substituted-amino]phenyl] pyridazinones and related compounds were synthesized and evaluated as inhibitors of cardiac cyclic AMP phosphodiesterase. Compounds 2c, 2d, 2h showed potent inhibitory activity and were found more potent than milrinone
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Piridazinas
/
Cardiotónicos
Idioma:
Inglés
Revista:
Egypt. J. Pharm. Sci.
Año:
1997
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