Compartive studies on the effect of bithionol, praziquantel and triclabendazole in rabbit's fascioliasis, 1 Parasitological studies

ABSTRACT

In this study, rabbits were infected with 30 metacercariae each. Then, they were divided into four categories, each of two groups. One category served as control and the others were treated each with a drug. The first group from each group was treated when worms were still immature, the other group was treated after maturity. The effect of the drugs was monitored by stool examination for eggs, the percentage of egg reduction and worm recovery at autopsy were studied and the percentage of the drug efficacy was calculated. Some eggs were cultured and their embryonation and hatching were traced. The results pointed out that triclabendazole was the best fasciolicide, followed by bithionol. Praziquantel had a negligible effect