Certain metabolic changes as influenced by five ovulatory steroids

ABSTRACT

Comparison between the effect of 5 oral ovulatory steroids namely Anovlar-1, Primovlar, Ovral, Microvlar-30 and Nordette proved that all the test contraceptives caused well marked increases in the level of total serum protein and blood urea of adult female albino rats. Short lasting increases were indicated in the level of serum albumin and creatinine. The level of uric acid was shortly disturbed only after anovlar-l and primovlar. Other compounds were devoid from any effect. The disturbances indicated was referred to estrogen/progestogen concentration, the metabolites of the progestogen as well as their structural configuration. The 4 months experimental period did not cause any significant fluctuations of these parameters determined in the corresponding control group