Effect of five ovulatory steroids on blood lipid levels

ABSTRACT

The daily oral administration of five ovulatory steroids namely Anovlar-1, Primovlar, Ovral, Microvlar-30 and Nordette for four months induced marked increase in serum total lipids, cholesterol and triglycerides. Phospholipids were not increased after Anovlar-1 and Nordette whereas, Ovral and Microvlar-30 caused a short last increase. Primovlar, on the other hand, induced significant elevations in phospholipids started two months after drug ingestion. The data proved that there was no relation between the magnitude of changes in lipid levels and the nature of estrogenprogesterone combination. Moreover, the synergistic effects could not be excluded