Study of direct and indirect tests of vasopressin function in diagnosis of diabetes insipidus

ABSTRACT

This study was conducted on 16 patients with diabetes insipidus [DI]. Direct and indirect tests of vasopressin function were performed for the patients and compared with ten matched control subjects. The study showed that the standard indirect test was enough for diagnosis of DI when present in its severe, complete and classic form. Yet, the need for plasma AVP assay becomes necessary to differentiate between the types of DI when present in partial or incomplete form due to the extensive overlap values obtained by the standard indirect test