Role of helicobacter in bile induced injury to gastric endothelium
New Egyptian Journal of Medicine [The]. 1997; 17 (4): 329-332
en Inglés
| IMEMR
| ID: emr-46305
ABSTRACT
Forty patients were included in this study [22 men and 18 women]. Patients showed variant forms of endoscopic findings ranging from normal finding to severe gastritis or duodenal ulcer. 24 patients [24/40] proved to be Helicobacter pylori [HP] positive by rapid urease test [60%]. Eighteen patients of them [18/24] were gram +ve [75%]. Patients showed bile reflux with bile acid> 1 mmol/I were 24 [24/40] of total [60%], 19 of them were HP positive by rapid urease test [79.1%], 16 of them were also gram +ve for HP, those 16 patients which were DGR +ve, urease +ve and gram +ve were subjected to treatment protocol of triple therapy for 2 weeks. Follow up was done after one month of the end of treatment. 10 patients with DGR showed marked reduction in bile acid concentration [<1 mmol/L], while the rest showed no changes. 13 patients became H. pylori -ve. All DGR -ve patients became H. pylori -ve [P> 0.05]. Histopathological examination of antral biopsy showed no inflammatory responses in 8 patients after eradication of H. pylori [n = 13]
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Bilis
/
Infecciones por Helicobacter
/
Endotelio
/
Mucosa Gástrica
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
New Egypt. J. Med.
Año:
1997
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