Primary glomerulonephritis and nephrotic syndrome in Pakistan

ABSTRACT

Renal diseases associated with proteinuria are known for centuries. OBJECTIVS To determine the pattern of primary glomerulonephritis in adult Pakistani nephrotics. DESIGN: Case study. Period 1986 - 1996. SETTING: Allied Hospital Medical Unit III Punjab Medical College Faisalabad. PATIENTS AND METHODS: 14 cases [Male - 10, Female - 4]. Male to female ratio 2.51. Membranous glomerulonephritis, minimal change glomerulonephritis, focal glomerulosclerosis and focal proliferative glomerulonephritis were 70%, 14%, 7% and 7% respectively. CONCLUSIONS: Sex involvement is similar all over the world. Minimal change glomerulonephritis and focal glomerulonephritis concide with incidence reported all over the world. Prevalence of membranous glomerulonephritis is similar to Western world but higher than Far East. Contrary to membranous glomerulonephritis prevalence of focal proliferative glomerulonephritis is very low in Pakistan as compared to China, Singapore and USSR