Bacterial pyogenic meningitis and drug sensitivity: one year study at peoples medical college, Nawabshah-Pakistan

ABSTRACT

To observe the causative microorganisms responsible for Bacterial Pyogenic Meningitis. Prospective and Retrospective study of 232 patients suffering from Bacterial Pyogenic Meningitis. Children and Medical wards of Peoples Medical College Hospital Nawabshah and Civil Hospital, Sanghar. Two hundred thirty two cases of Bacterial Pyogenic Meningitis with different age groups from neonates to old subjects. Main outcome measures: Clinical features of patient-Biochemical examination of C.S.F. and Culture and sensitivity test. The organisms isolated were in order of frequency, N. meningitidis 51.7%. Strept, pneumonia 43.1%, H. influenzae 4.3% Strept. agalactiae 0.43% and that 70-90% isolates were sensitive to Penicillin G, Ampicillin, Chloramphenical and Co-trimoxazole [Septran]. However 90-100% of these isolates were sensitive to 3rd generation antibiotics. In Bacterial Pyogenic Meningitis most common microorganisms are Strept, pneumonia, N. meningitidis and H. influenzae