Prevalence of helicobacter pylori in a tertiary care hospital in Peshawar, Pakistan

ABSTRACT

To find out prevalence of Helicobacter pylori in tertiary care hospital in Peshawar. Design: A prospective study of 100 dyspeptic patients referred to the Department of Gastroenterology. Setting: Department of Gastroenterology / PGMI, LRH, Peshawar. Subjects: Hundred Dyspeptic patients. Mai/n Outcome Measures: The incidence of Helicobacter pylori in this study is the same as that shown in other parts of the world with only minor differences in gastritis and a significant association with carcinoma stomach. The maximum number of patients were between 41 -60 years with 72% males. Most of the patients presented with epigastric pain, followed by dyspeptic symptoms, recurrent vomiting, weight loss, anaemia and abdominal mass in that order of frequency. Duodenal ulcer was the most common underlying pathology [36%]. Out of 100 patients seventy four [74%] were positive for Helicobacter pylori. Out of these 74 [74%] positive cases, 34 [94.4%] had duodenal ulcer, followed by 1 3 [81.25%] with gastritis, 6 [60%] with gastric ulcer, 4 [40%] with reflux oesophagitis and 3 [50%] had carcinoma stomach. Conclusions: This study shows that the prevalence of Helicobacter pylori compares well with documented studies in those with dyspepsia excepting an increased incidence of gastritis and gastric carcinoma