13C and 1H nuclear magnetic resonance spectral studies on some 1,4-disubstituted piperazine derivatives

ABSTRACT

[13]C AND [1]H chemical shifts are reported for a number of 1-[p-substituted phenacyl]-4-arylpiperazine analogues. The present NMR data clearly demonstrate the easy distinction of these analogues utilizing [13] C NMR. A similar differentiation using [1]H NMR was not possible as some of these analogues displayed complex and overlapping proton resonances particularly in the aromatic region. Thus, in the present study emphasis has been given to the [13]C NMR assignments. The methods and techniques followed for the assignments are described