effect of rehydragel and saponin as adjuvant on the immune response of horses vaccinated with inactivated AHS vaccine

ABSTRACT

Two types of binary inactivated AHS vaccines using rehydragel with or without saponin as adjuvants were prepared from virus serotype 9. Two groups [each of two horses] received either the inactivated rehydragel without saponin or the inactivated rehydragel with saponin vaccine separately. A second dose [boostering dose] was administered 30 days after the first one. Sera were collected every 15 days till the end of the experiment [8months] and was tested serologically [ELISA and SNT] to measure the developed immune response which was higher in horses vaccinated with the inactivated rehydragel vaccine with saponin as adjuvant than the other two horses