Cyclospora: a newly identified protozoan pathogen of man

A newly recognized protozoan human parasite, Cyclospora spp., has been incriminated as the cause of prolonged diarrhea. It has been isolated from children, immunocompetent and immunocompromised adults. 130 immunocompetent patients [80 children and 50 adults] were included in this study, their illness was characterized by prolonged watery diarrhea, were enrolled in this study. Stool sediments were examined as wet mounts and stained by both modified Ziehl-Neelsen and aniline carbol methyl violet stains. The protozoan pathogen was identified as spherical bodies measuring 9-10 mum in diameter in about 9% and 10% in both children and adult groups, respectively. The mean duration of illness was 28 +/- 8 and 37 +/- 12 days and the frequency of stool motions was >5/day with normal mucosal pattern on colonoscopic studies for adults group. It was concluded that cyclosporiosis is quite similar to cryptosporidiosis and both oocysts have the affinity to acid fast stain. So, the present recommendations for all laboratories screening stool for cryptosporidia should measure the oocyst to distinguish between these different parasites