Human chronic fascioliasis: Hepatitis B and C among infected cases

ABSTRACT

Sera from one hundred and fifty three chronic Fasciola cases were screened for the presence of HB markers [HBsAg, anti HBc and anti HBs] and anti HCV using ELISA technique. Quantitative stool examination and estimation of liver enzymes [AST-ALT-bilirubin] levels of the study population were performed. HBsAg was present in 5 [3.3%], anti HBs in 13 [8.5%], HBexposed [HBex] in 44 [28.8%] and anti HCV in 13 [8.5%] of examined sera. HBV and HCV markers were significantly higher among older age groups. Concerning familial aggregation of hepatitis markers, 7 [15.9%] of the 44 HBex cases had two individuals per family who had evidence of exposure to HBV. No significant change in Fasciola GMEC and liver function tests have been noticed