Effet du regime hypercholesterolenique et vitamine D2 surle developpement de l'atherosclerose chez le rat [psammomys obesus] vivant au Maroc

ABSTRACT

Our study was performed on 32 sand rats living in Morocco [Psammomys obesus] a specimen which is predisposed to develop obesity type II when given a hypercaloric cholesterol enriched and diabetic diet. Some of these animals received vitamin D2 orally in a high dosage. Two [2] months later, we observed different types of injuries especially macroangiopathy in which the atheromatous lesions were enhanced by addition of vitamin D2. These results are correlated to the biochemical findings especially high levels of LDL cholesterol