Histopathology of lymph nodes of babesia infected cattles with estimation of adenosine deaminose activity in blood cells and serum

ABSTRACT

The present work was carried out on cattles infected with Babesia bigemina. Blood examination showed various forms of the parasite intraerythrocytes. The histopathological study of the lymph nodes revealed follicular hyperplasia and marked dilatation and congestion of the medullary blood sinusoids with parasitized and non-parasitized RBCs. The activity of adenosine deaminase [ADA] was determined in erythrocytes, leukocytes and serum of infected cattles with acute babesiosis. ADA activity was significantly increased in both erythrocytes and serum, while leukocyte ADA activity showed a significant decrease indicating suppression of cell-mediated immunity