Ovarian hormones correlate antomical cyclic changes in teenage girls

ABSTRACT

Changes in the levels of steroid hormones and the size of ovarian contents during menstrual cycle of 102 healthy teenage girls investigated. Serum progesterone and estradiol levels were measured by their respective serozyme EIA method and the corresponding anatomical cyclic changes were visualized through ultrasonography. Like other studies, serum progesterone levels were found to be high during the luteal phase, whereas mean estradiol level before ovulation was 105.8 pg/ml and after ovulation, 91.8 pg/ml. size of follicle increased during proliferative phase, thus had positive correlation with estradiol level in the first phase [correlation co-efficient 0.7and covariance 42]. While corpus luteum was seen during secretory phase and had fairly good correlation with concurrent serum progesterone level in the same phase [correlation co-efficient 0.8 and covariance 35]. Hence, it concluded that estradiol level can correlate well with the structural changes in the follicle during the first phase and progesterone level coincides with the size of corpus luteum during the second phase of the menstrual cycle in teenage girls. Besides, minimum level of estradiol on day 13 [68 pg/ml] required for ovulation and indicating ovulation respectively in our community