Pattern of colorectal carcinoma at Larkana

ABSTRACT

A total of 105 cases of colorectal carcinoma were studied, from January 1993 to December 1997 at the histopathology section of the Department of Pathology, Chandka Medical College, Larkhana. Male to female ratio in the study was 2.081. Ages of the patients ranged from 12 to 75 years with mean age of 44.63 years, which was higher in females [46.32 years] than in the males [43-83 years]. Most patients were seen between 3rd to 5th decade of life [70.5%] with peak age in the 5th decade [26.7%]. Most of the tumours were located in rectum, caecum and sigmoid colon in descending order of frequency. Left colon was more commonly involved than the right with male to female ratio higher in the former than in the latter. The most common histological type of carcinoma was adenocarcinoma diagnosed in 87 [82.87%] cases followed by mucinous variant in 15 [14.28%] cases. The most common presenting complaints of patients were abdominal pain and bleeding per rectum. History of haemorrhoids was present in 7 [6.66%] cases and inguinal lymphadenopathy in 15 [14.28%] cases. It was observed that colorectal carcinoma in the present study was in many respects similar to that reported from other pans of the country and from abroad but regarding the age, our patients were much younger than their western counter parts