Different gynecological and endometrial pathologies in post menopausal breast cancer patients treated with tamoxifen

ABSTRACT

In the present study, the histopathological conditions diagnosed in endometrium, myometrium and ovaries of 28 postmenopausal breast cancer patients treated with tamoxifen [study group] were assessed and their findings were compared with those obtained from 14 similar patients without tamoxifen treatment [control group I] and 28 age-matched healthy postmenopausal controls [control group II]. The results obtained suggested that there might be an association between the postmenopausal tamoxifen exposure and the development of different coexisting or specific single gynecological pathologies originating from the endometrium