Role of mitomycin C as an adjuvant to endoscopic resection of superficial bladder tumours

ABSTRACT

An experience in 171 cases of suuperficial urinary bladder tumors treated with transurethral resection [TURT] at the Mayo Hospital Lahore between 1985 to 1990 is reported. In 160 cases out of 171, the tumors were resected endoscopically followed by intravesical instillation of Mitomycin-C 20mg. This resulted in significant reduction in the number of recurrences. In the remaining 11 cases, the tumors were too numerous for endoscopic resection. In these cases the intravesical Mitomycin-C 20mg twice weekly for 4 weeks resulted in marked improvement and the tumors were either rendered resectable or disappeared completely