Normal prediction equations of spirometric parameters in 799 healthy Iranian children and adolescents

ABSTRACT

There are no available native reference values for pulmonary function tests in Iran. A study was carried out in Isfahan to develop prediction equations of ventilatory function for normal children and adolescents based on age and height. The data for healthy individuals aged between 4 to 18 [357 girls and 442 boys] were extracted from a larger study of spirometric measurements collected from 2,602 individuals studied at medical services in Isfahan, Iran. Several models were tested for the prediction of FEV1, FVC and the FEV1/FVC ratio. Using multiple regression analysis, many equations were tested and the best models were selected for each gender. In children, the best models were those using linear regression with age and height [r2=0.86-0.94]. In children, pulmonary function can be efficiently predicted, based on age and height, by using appropriate equations