Some aspects of drug interaction A Hematological and histopathological changes of rabbit's uteri experimentally treated with progesterone and diazinon

ABSTRACT

The haematological picture and the histopathological changes of rabbit's uteri treated with 1.5mg progesterone and 10 25, 50 mg/ Kg B.W.diazinon were investigated. There was a decrease in the amount of haemoglobin, and the number of red cells, leucocytes, heterophils and lymphocytosis in rabbits treated with diazinon and with progesteron and the higher doses of diazinon. The uteri of the latter treated animals showed atrophy of the endometrium. There was an antagonistic action between prgesterone and diazinon