Age-related response to noise stress on gastric secretion and ulceration in male albino rats

ABSTRACT

The effects of noise on gastric secretion and ulceration in male albino rats were investigated. Forty-eight rats were used and divided into three main groups i.e. young, adult and senile. Each group was subdivided into control and experimental subgroups. The experimental animals were exposed to noise stress [100 dB] one hour daily for four weeks. The results showed that noise decreased the volume and total acid output in all animal groups and increased the titratable acidity in young group. Noise increased the ulcer index in adult and senile groups and led to vascular congestion, inflammatory cell infiltration, glandular deformity, mucosal atrophy and musculosa hypertrophy in the stomach of all groups