Prevalence of urinary tract tuberculosis among cases of chronic urinary tract infection in a tertiary care hospital

ABSTRACT

Prevalence of urinary tract tuberculosis among patients suffering from chronic urinary tract infection reporting to a tertiary care hospital was determined. Three hundred patients with ages between 15-70 years of both sexes [male, n = 198; female, n = 102] were included. All the cases were suffering from recurrent and chronic urinary tract infection. Twenty four hours urine specimens for acid fast bacilli culture were collected and inoculated on Lowenstein Jensen [LJ] media. The antibiotic sensitivity was performed on LJ media with antibiotics using agar dilution method. H37 Rv strain of M.tuberculosis was used as control to determine the resistant ratio. The patients were given 4 first line anti tuberculosis drugs, namely Isoniazid [INH], Rifampicin [RIF], Ethambutol and Pyrazinamide. Twenty four [8%] cases revealed positive culture for M. tuberculosis. Twenty isolates were susceptible to all the 4 drugs. Two isolates were multi drug resistant M. tuberculosis. Two isolates revealed resistance to either RIF or INK All the patients responded to treatment given. Urinary tract tuberculosis should always be considered in cases of chronic urinary tract infection, particularly when they are not relived by antibiotic therapy