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Role of cytokines as markers for immunomodulation in patients with hepatitis C
Bulletin of High Institute of Public Health [The]. 2002; 32 (4): 833-846
en Inglés | IMEMR | ID: emr-59046
ABSTRACT
In the present study, soluble interleukin-2 receptor [sIL-2R] and tumor necrosis factor-alpha [TNF-a] were measured in serum by ELISA and alpha fetoprotein was assessed by RIA in 20 patients with hepatitis C virus [HCV] infection, in addition to 10 apparently healthy subjects served as controls. The results showed an increased serum level of sIL-2R in the patients group [783.65 U/ml] than in the control subjects [774.19 U/ml]. In the same time, the mean level of TNF-alpha was also significantly elevated in patients [1.51 +/- 1.01] than in the controls [0.39 +/- 0.07 ng/ml]. Furthermore, 3 out of 20 HCV +ve patients had an elevated serum alpha-fetoprotein [AFP]
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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Ensayo de Inmunoadsorción Enzimática / Radioinmunoensayo / Receptores de Interleucina-2 / Alfa-Fetoproteínas / Adyuvantes Inmunológicos / Citocinas / Factor de Necrosis Tumoral alfa Tipo de estudio: Ensayo Clínico Controlado Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Bull. High Inst. Public Health Año: 2002

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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Ensayo de Inmunoadsorción Enzimática / Radioinmunoensayo / Receptores de Interleucina-2 / Alfa-Fetoproteínas / Adyuvantes Inmunológicos / Citocinas / Factor de Necrosis Tumoral alfa Tipo de estudio: Ensayo Clínico Controlado Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Bull. High Inst. Public Health Año: 2002