prophylactic effect of vegetable and fruit fibers and wheat bran on serum glucose, lipid profile and liver functions of rats feed hyperlipidemic diet

ABSTRACT

The aim of this work was to study the effect of dietary fiber sources like fruit fiber [apple peels], vegetable fiber [bean pods], cereal fiber [wheat bran] on serum glucose, lipid profile and liver functions of rats fed hyperlipidemic diet compared with nutraceutical bran capsules as well as positive and negative controls. Vegetables fiber, fruits fiber and wheat bran reduced the increase of serum glucose, total cholesterol, triglycerides, low density lipoprotein [LDL], very low density lipoprotein [VLDL], risk ratio and also declined liver enzymes activity; while, they increased serum high density lipoprotein- cholesterol of rats fed on hyperlipidemic diets compared with a positive control group. The dietary fiber gave better results compared with nutraceutical bran capsules in the aforementioned measurements. Lowest increasing percentages were obtained after eight weeks in the level of glucose, triglycerides, total cholesterol, risk ratio, LDL, VLDL, aspartate amino transferase [AST] and alanine amino transferase [ALT] where the values were 11.92, 45.3, 62.5, 37.5, 240.3, 45.5, 10.0 and 7.9%, respectively, in the serum of rats fed on dietary fiber sources, where the values were 24.13. 122.3, 46.5, 240.3, 257.0, 38.3 and 37.0% in the rats of the positive control group, respectively, as well as 10.72, 192.3, 37.4, 9.4, 22.3, 192.3, 10.0 and 10.3% in rats fed on diet contained nutraceutical bran capsules, respectively