Endogenous inhibitor [S] of platelet aggregation

ABSTRACT

Human blood plasma contains an endogenous inhibitor [s] of platelet aggregation [EIPA]. The EIPA activity was found to be associated with alpha - globulin-rich and albumin-rich protein fractions of blood plasma. Data presented in this paper suggests that EIPA may regulate platelet aggregation associated with excessive production of arachidonic acid metabolites