Premenstrual manic disorder: review of literature, case report and the efficacy of trifluoperazine

ABSTRACT

A selective review of literature revealed only a few case reports of premenstrual mania, hereto referred as premenstrual manic disorder [PMMD]. The anamnesis of a woman who developed manic episodes, one week before each menstrual cycle that used to remit after the onset of menstruation, is described. The continuing use of trifluoperazine satisfactorily improved her premenstrual manic symptoms and also prevented the subsequent premenstrual manic relapses. In addition to proposing tentative research criteria of PMMD, its underlying etiological mechanisms together with treatment perspectives are discussed comprehensively