Evaluation of granulocyte-colony stimulating factor and neutrophil count in term neonates born to mothers with pregnancy induced hypertension

ABSTRACT

The objective of this study was to estimate the cord blood levels of granulocyte-colony stimulating factor [G-CSF] in term infants born to mothers suffering from pregnancy induced hypertension [PIH] and to study its relation with neonatal neutrophil count and maternal mean arterial blood pressure. G-CSF in the PIH group was significantly lower than the control group, while neutrophil count was not different in the PIH and control groups. Only two infants in the PIH group had marked neutropenia. No definite correlations were found between maternal mean arterial blood pressure and fetal neutrophil count or fetal G-CSF. Also, fetal neutrophil count was not correlated with fetal G-CSF