reproductive status affects the oxytocin-mediated natriuresis in conscious male rats during dehydration

ABSTRACT

The present study was undertaken to investigate whether oxytocin is a possible mediator in these mechanisms by examining its role in dehydration-natriuresis in conscious male rats. It was concluded from this study that oxytocin may participate in natriuretic mechanisms for sodium regulation during the short periods of water deprivation and that the reproductive status do influence the renal responsiveness to oxytocin indicated by the augmentation of this response after testosterone treatment in animals with orchidectomy