Analgestic and antipyretic activity of fruits of Marynia annua Linn.

ABSTRACT

The petroleum ether, chloroform, ethanol and aqueous extracts of Martynia annua Linn. [Fam. Martyniaceae] fruits were studied for analgesic activity on Swiss albino mice using Hot Plate and Tail Flick methods. The extracts were also screened for antipyretic activity by brewer's yeast induced hyperpyrexia model on adult wistar rats. The results were compared with diclofenac sodium. All the extracts showed significant analgesic and antipyretic activity when compared to the standard drug with a lone observation that the degree of activity of the petroleum ether and chloroform extracts are better than the ethanol and aqueous extracts. The present findings suggest that the fruits of the plant are endowed with potential analgesic and antipyretic properties