Microalbuminuria and associated risk factors in type II diabetics

ABSTRACT

To determine the frequency of microalbuminuria [MA] and its associated medical risk factors in type II diabetic patients. Place and Duration of Study This cross-sectional analytical study was conducted during Ist half of 2003 at Combined Military Hospital, Lahore. Non-probability purposive sampling was employed. Materials and Study population included 150 type II diabetic patients [70 women, 80 men] attending outpatient department of the hospital. Patients having clinical albuminuria and with other causes of proteinuria were excluded. Women and men were of comparable ages. Women [26.4 kg/m2] had higher body mass index [BMI] than men [24.3 kg/m2]. The frequency of MA was 46.7%, higher in males [50.6%] than females [41.5%]. Fasting plasma glucose and HbA1c levels were significantly higher in patients with MA compared to those with normoalbuminuria [p < 0.001]. The microalbuminuric patients had significantly decreased HDL-c levels compared to normoalbuminuric subjects [p< 0.001]. However, no relation of MA with age, gender, known duration of diabetes, BMI, history of smoking, hypertension and serum total cholesterol, LDL-c, triglyceride, urea and creatinine was found. There is a strong association of poor glycaemic control and decreased HDL-c levels with the presence of microalbuminuria