[Necrotizing histiocytic lymphadenitis report of two cases [Kikuchi Fujimoto disease]]

ABSTRACT

Kikuchi Fujimoto disease is a Necrotizing lymphadenitis with benign self-limit process in young women with fever, cervical lymphadenopathy and increased ESR with leukopenia. In this report we introduce two females with Kikuchi Fujimoto disease. The first patient was a 31 years old lady with fever and unilatral cervical lymphadenopathy weight loss from 20 days age. In para-clinical findings ESR=50mm/hr Hb= 10gr/dl. WBC count was 5300/microl bone marrow aspiration and biopsy with lymph node was done. The histopathologic diagnosis was Kikuchi Fujimoto [Necritizing Lymphadenitis]. The second patient was a lady with 35 years old and painful neck mass [behind the sterno-clido mastiod] from 1.5-month age with fever and chill. In paraclinical findings ESR=52 mm/hr WBC 5500/microl, CRP++ lymph node biopsy was done the histopathologic diagnosis was Kikuchi Fujimoto Necrotizing Lymphadenitis. Therefore Kikuchi disease is an important differantial diagnosis in young patients especially women with cervical lympadenopathy and fever [F.U.O]