Helicbacter pylori clearance and eradication with triple therapy in duodenal ulcer patients

ABSTRACT

Triple therapy was given to 49 chronic helicobacter pylori positive chronic duodenal ulcer cases to see its efficacy in H. pylori clearance, eradication and ulcer healing. H. pylori clearance and eradication rates at weeks 5 and 8 were 87.8 percent and 81.5 percent while ulcer healing rates 68.2 percent and 81.5 percent respectively. Seven [18 percent] cases failed to clear H. pylori and were classified as non-responders. Histologically 60 percent showed post-treatment regression of gastritis. Tolerance to drugs was excellent with a good compliance rate