Skull metastasis as the first presentation of hepatocellular carcinoma

ABSTRACT

Skull metastasis from Hepatocellular carcinoma, specially as the first presentation is very rare. We report a case with a history of head trauma in Bam earthquake and craniotomy due to lytic tumor of the skull, presented with upper gastrointestinal symptoms which Hepatocellular carcinoma with skull metastasis was revealed .the patient was infected with hepatitis B virus without cirrhosis