Histopathological changes in aborted fetuses infected with brucella organism

ABSTRACT

To study the pathological effect of Brucella organism on the organ's tissues of aborted sheep fetuses, 15 aborted fetuses were used. Brucella organisms were isolated and the fetuses which were positive, their organs were used for pathological study. Then Brucella was isolated from 12 aborted fetuses, examination showed that Br. abortus was the main cause of abortion [percentage 75%], while Br. melitensis was 25%. The histological exam to the organ's of the aborted fetuses which were infected with brucellosis showed that the main organs affected were as follow- The Brain/ The lesions that were noticed are, diffuse haemorrahges, focal gliosis and neutrophils infiltration within the parenchyma which was in some spots disappeared. The Lungs/ Interstitial pneumonia represented by alveolar blood vessels congestion with inflammatory cells infiltration leading to alveolar wall thickness. The Liver/ Enlargement of the hepatic sinusoids which are filled with blood, the congestion of the central veins with inflammatory cells infiltration especially the neutrophils, also the focuses of small lymphocytic aggregates, and in some cases there was broad degenerative changes in the hepatic tissue. The Kidneys/ Interstitial nephritis represented by the monocytes infiltration especially lymphocytes within the interstitial tissue between the glomerulius and the renal tubules with congestion of the blood vessels and necrotic changes in the renal tubules. The Spleen/ Lymphoid hyperplasia of white pulp and inflammatory cells infiltration within the red pulp. The Testis/ Huge inflammatory cells infiltration especially lymphocyts and neutrophils leading to capsule thicknesses and there is some necrotic and degenerative changes in the seminal tubules. The Heart/ The histological exam of heart muscles showed no significant pathological changes